Cilastatin molecular weight

http://editor.fresenius-kabi.us/PIs/US-PH-Imipenem-and-Cilastatin-for-Inj-USP-FK-451205C-05-2015-PI.pdf WebSep 4, 2024 · Imipenem / Cilastatin Formulation Version 8.0 Revision Date: 23.08.2024 SDS Number: 15841-00026 Date of last issue: 09.04.2024 Date of first issue: 05.11.2014 7 / 16 Explosive properties : Not explosive Oxidizing properties : The substance or mixture is not classified as oxidizing. Molecular weight : No data available

Primaxin (cilastatin sodium and imipenem) vial label

WebAdditional Names: Cilastatin sodium Molecular Formula: C16H25N2NaO5S Molecular Weight: 380.43 Percent Composition: C 50.51%, H 6.62%, N 7.36%, Na 6.04%, O 21.03%, S 8.43% Properties: Off-white to yellowish-white hygroscopic, amorphous solid. pKa1 2.0; pKa2 4.4; pKa3 9.2. Very sol in water, methanol. pKa: pKa1 2.0; pKa2 4.4; pKa3 9.2 WebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, respectively, approximately 3.2 and 1.9 times the RHD (based on body surface area). ... It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of … raymond st jacques cause of death https://gomeztaxservices.com

Primaxin IM (Imipenem and Cilastatin): Uses, Dosage, Side …

Webwhite, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C. 12. H. 17. N. 3. O. 4. S•H. 2. O, and its structural . formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid. Its chemical name is sodium (Z ... WebOct 6, 2024 · It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of 380.43. It is very soluble in water and in methanol. Its empirical formula is C 16 H 25 N 2 O 5 SNa, and its structural formula is: Imipenem and Cilastatin for Injection, USP (I.V.) is buffered to provide solutions in the pH range of 6.5 to 8.5. WebJan 12, 2024 · Additionally, body weight loss due to cisplatin was not affected by cilastatin (supplementary Fig. 1C). Figure 1 Administration of cilastatin suppressed cisplatin-induced kidney injury. simplify 83

Cilastatin - an overview ScienceDirect Topics

Category:Cilastatin CAS#:82009-34-5 Chemsrc

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Cilastatin molecular weight

Primaxin I.V. (Imipenem and Cilastatin for Injection): Uses, …

Weboff-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water, and slightly soluble in methanol. Its empirical formula is C 12H 17N 3O 4S•H 2O, and its structural formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid. Its chemical name is [R-[R*, S*-(Z)]]-7- Web199 rows · Aug 29, 2007 · The total clearance of imipenem is 0.2 L/h/kg. 8 When used alone, the renal clearance is 0.05 L/h/kg. In combination with cilastatin the renal …

Cilastatin molecular weight

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Webwhite, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is … WebAug 20, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water, and slightly soluble in methanol. Its …

WebThe following data is based on the product molecular weight 358.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which … WebCilastatin C16H26N2O5S CID 6435415 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ...

WebTrade name:Cilastatin (Contd. from page 4) 53.1.21 · Molecular Weight 358.5 g/mol · Odor threshold: Not determined. · pH-value: Not applicable. · Change in condition Melting point/Melting range: Undetermined. Boiling point/Boiling range: Undetermined. · Flash point: Not applicable. · Flammability (solid, gaseous): Product is not flammable. WebCilastatin. Monograph ID M3544 Title Cilastatin UNII 141A6AMN38 Molecular formula C 16 H 26 N 2 O 5 S Molecular weight 358.45 Percent composition C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.94% Standard InChI

WebCilastatin sodium, Tocris Bioscience™ Structure Search; Print Cilastatin sodium, Tocris Bioscience™ Click to view available options ... Molecular Weight (g/mol) 380.435: InChI Key: QXPBTTUOVWMPJN …

WebFeb 15, 2016 · Antimicrobial stewardship programs (ASPs) focus on improving the utilization of broad spectrum antibiotics to decrease the incidence of multidrug-resistant Gram positive and Gram negative pathogens. Hospital admission for both medical and surgical intra-abdominal infections (IAIs) commonly results in the empiric use of broad spectrum … simplify 8 - 30 ÷ 6 +7WebAug 3, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, ... Cilastatin sodium was given intravenously to rabbits at doses up to 300 mg/kg/day and to rats subcutaneously at … simplify 8/27WebCilastatin Molecular Formula CHNOS Average mass 358.453 Da Monoisotopic mass 358.156250 Da ChemSpider ID 4940183 - Double-bond stereo - 2 of 2 defined stereocentres More details: Featured data source … simplify 8/28raymond st maple heightsWebThe mean serum half-life of imipenem is about 2 hours, whereas that of cilastatin is 5 to 6.4 hours [488]. The half-life for both drugs is inversely related to birth weight and … raymond stockwellWebCilastatin(MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Quality confirmed by NMR & HPLC. See customer reviews, validations & product … simplify 8 3 . 192 24 512WebName: Cilastatin CAS#: 82009-34-5 (free acid) Chemical Formula: C16H26N2O5S Exact Mass: 358.15624 Molecular Weight: 358.45 Elemental Analysis: C, 53.61; H, 7.31; N, 7.82; O, 22.32; S, 8.95 Price and Availability Technical data Biological activity Solubility and formulation Protocols Calculators References simplify 83 1/3 over 100